AntimicrobialAlso known as: LfcinB, bovine lactoferricin, f(17-41)
Lactoferricin B
Antimicrobial peptide derived from pepsin cleavage of bovine lactoferrin (amino acids 17-41) — more potent than the parent protein. Broad-spectrum activity against bacteria, fungi, parasites, and some tumor cells.
Half-Life
~1-2 hours (estimated)
Dose Range
50-250 mcg (research)
Frequency
Per study protocol
Vial Sizes
5 mg
Mechanism of Action
Amphipathic β-hairpin loop with net positive charge (+8) that disrupts microbial membrane integrity via electrostatic binding to LPS and lipoteichoic acid. Also triggers apoptosis in cancer cells via mitochondrial membrane depolarization.
Source: PMID: 18721608
Dosing Protocol
| Typical Dose | 50-250 mcg (research) |
| Frequency | Per study protocol |
| Half-Life | ~1-2 hours (estimated) |
| Common Vial Sizes | 5 mg |
Reconstitution Example
Vial
5 mg
Water
2 mL
Concentration
2.5 mg/mL
Per Unit (100u syringe)
25 mcg
Dose of 50 mcg = 2 units on a 100-unit insulin syringe
Dosing Quick Reference
Lactoferricin B— Dosing Guide
Dose Range
50-250 mcg (research)
Half-Life
~1-2 hours (estimated)
Frequency
Per study protocol
Route
Subcutaneous
5 mg vial
💧 2 mL BAC water|📐 2.5 mg/mL concentration|💉 25 mcg/unit (100u syringe)
Antimicrobialcalcmypeptide.com
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